Table 4.
Serum enzymatic findings (U/L), in rats treated with saline, olive oil, silymarin, doxorubicin and combination of silymarin and doxorubicin.
| ALT | AST | LDH | CK | |
|---|---|---|---|---|
| ConS | 40.03 ± 3.4 | 270 ± 85.7 | 998 ± 129 | 316 ± 104 |
| ConO | 43.3 ± 5.8 | 299 ± 131.74 | 1012 ± 215 | 323 ± 76 |
| Sil | 49.8 ± 3.5 | 198.8 ± 32.69 | 946 ± 117 | 279 ± 89 |
| Dox | 60 ± 25.5 | 349.6 ± 71.5 a | 2325 ± 343 c | 616 ± 39 b |
| DoxSil | 58.5 ± 12.4 | 279.5 ± 47.5 | 1843 ± 487 d | 402 ± 81 |
a p < 0.05 compared to ConS, Sil and DoxSil; b p < 0.01 compared to ConS, ConO, Sil, DoxSil; c p < 0.01 compared to ConS, ConO and Sil; d p < 0.05 compared to Sil; n = 6; mean ± SD.