Table 2.
Inhibition activities of some 3-substituted-indolin-2-ones on VEGFR2.
| Compd. | IC50 ± SD (nM) | Compd. | IC50 ± SD (nM) |
|---|---|---|---|
| 14c | 6.8 ± 1.8 | 14i | 11.2 ± 2.6 |
| 14f | 6.2 ± 0.8 | 14p | 6.0 ± 1.2 |
| 14g | 5.0 ± 1.1 | 14r | 8.7 ± 1.3 |
| 14h | 6.8 ± 0.8 | Sunitinib | 6.5 ± 3.0 |
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