Table 2.
The mean MICs and MBCs of MSKE and its phenolic principles against S. aureus ATCC 25923 and 19 clinically isolated MRSA strains (a mean values ± S.D. of triplicate results, b mean values ± S.D. from 19 MRSA strains).
| Bacterial strains | Susceptibility of Bacteriaa | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MSKE (mg/mL) | PGG (mg/mL) | MG (mg/mL) | GA (mg/mL) | Vancomycin (µg/mL) | Penicillin G (µg/mL) | |||||||
| MIC | MBC | MIC | MBC | MIC | MBC | MIC | MBC | MIC | MBC | MIC | MBC | |
| S. aureus ATCC 25923 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.13 ± 0.00 | 0.50 ± 0.00 | 0.38 ± 0.00 | 1.00 ± 0.00 | 0.19 ± 0.00 | 0.75 ± 0.00 | 0.78 ± 0.00 | 3.13 ± 0.00 | 41.67 ± 18.04 | 41.67 ± 18.04 |
| Clinical MRSA strains | ||||||||||||
| M 01 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.17 ± 0.07 | 1.00 ± 0.00 | 1.25 ± 0.43 | 1.50 ± 0.00 | 0.25 ± 0.11 | 0.75 ± 0.00 | 1.56 ± 0.00 | 6.25 ± 0.00 | 2,000.00 ± 0.00 | 8,000.00 ± 0.00 |
| M 02 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.17 ± 0.07 | 1.00 ± 0.00 | 1.00 ± 0.43 | 1.25 ± 0.43 | 0.38 ± 0.00 | 0.63 ± 0.22 | 1.56 ± 0.00 | 6.25 ± 0.00 | 2,000.00 ± 0.00 | 5,333.33 ± 2,309.40 |
| M 03 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.13 ± 0.00 | 1.00 ± 0.00 | 1.25 ± 0.43 | 1.25 ± 0.43 | 0.38 ± 0.00 | 0.63 ± 0.22 | 1.56 ± 0.00 | 6.25 ± 0.00 | 2,000.00 ± 0.00 | 4,000.00 ± 0.00 |
| M 04 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.13 ± 0.00 | 1.00 ± 0.00 | 1.25 ± 0.43 | 1.25 ± 0.43 | 0.25 ± 0.11 | 0.50 ± 0.22 | 1.56 ± 0.00 | 6.25 ± 0.00 | 1,333.33 ± 577.35 | 2,666.67 ± 1,154.70 |
| M 05 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.13 ± 0.00 | 1.00 ± 0.00 | 1.25 ± 0.43 | 1.50 ± 0.00 | 0.38 ± 0.00 | 1.00 ± 0.43 | 1.56 ± 0.00 | 6.25 ± 0.00 | 2,000.00 ± 0.00 | 5,333.33 ± 2,309.40 |
| M 06 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.17 ± 0.07 | 1.00 ± 0.00 | 1.25 ± 0.43 | 1.25 ± 0.43 | 0.25 ± 0.11 | 0.38 ± 0.00 | 1.56 ± 0.00 | 12.50 ± 0.00 | 1,666.67 ± 577.35 | 4,000.00 ± 0.00 |
| M 07 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.17 ± 0.07 | 1.00 ± 0.00 | 1.25 ± 0.43 | 1.75 ± 1.15 | 0.63 ± 0.22 | 0.75 ± 0.00 | 1.56 ± 0.00 | 6.25 ± 0.00 | 2,000.00 ± 0.00 | 8,000.00 ± 0.00 |
| M 08 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.17 ± 0.07 | >1.00 ± 0.00 | 1.25 ± 0.43 | 1.25 ± 0.43 | 0.38 ± 0.00 | 0.38 ± 0.00 | 1.56 ± 0.00 | 6.25 ± 0.00 | 1,666.67 ± 577.35 | 4,000.00 ± 0.00 |
| M 09 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.17 ± 0.07 | 1.00 ± 0.00 | 1.25 ± 0.43 | 1.25 ± 0.43 | 0.38 ± 0.00 | 0.38 ± 0.00 | 1.56 ± 0.00 | 12.50 ± 0.00 | 1,666.67 ± 577.35 | 4,000.00 ± 0.00 |
| M 10 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.17 ± 0.07 | >1.00 ± 0.00 | 1.25 ± 0.43 | 1.50 ± 0.00 | 0.63 ± 0.22 | 0.75 ± 0.00 | 1.56 ± 0.00 | 6.25 ± 0.00 | 1,666.67 ± 577.35 | 8,000.00 ± 0.00 |
| M 11 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.17 ± 0.07 | 1.00 ± 0.00 | 1.50 ± 0.00 | 1.50 ± 0.00 | >3.00 ± 0.00 | >3.00 ± 0.00 | 1.56 ± 0.00 | 12.50 ± 0.00 | 2,000.00 ± 0.00 | 8,000.00 ± 0.00 |
| M 12 | 0.47 ± 0.00 | 3.75 ± 0.00 | 0.13 ± 0.00 | >1.00 ± 0.00 | 2.50 ± 0.87 | 2.50 ± 0.87 | >3.00 ± 0.00 | >3.00 ± 0.00 | 1.56 ± 0.00 | 12.50 ± 0.00 | 4,000.00 ± 0.00 | 8,000.00 ± 0.00 |
| M 13 | 0.47 ± 0.00 | 3.75 ± 0.00 | 0.17 ± 0.07 | 1.00 ± 0.00 | 0.75 ± 0.00 | 1.00 ± 0.43 | 0.25 ± 0.11 | 0.75 ± 0.00 | 6.25 ± 0.00 | 12.50 ± 0.00 | 8,000.00 ± 0.00 | 8,000.00 ± 0.00 |
| M 14 | 0.47 ± 0.00 | 0.94 ± 0.00 | 0.13 ± 0.00 | 1.00 ± 0.00 | 1.25 ± 0.43 | 1.25 ± 0.43 | 0.63 ± 0.22 | 0.75 ± 0.00 | 3.13 ± 0.00 | 12.50 ± 0.00 | 4,000.00 ± 0.00 | 8,000.00 ± 0.00 |
| M 15 | 0.47 ± 0.00 | 0.94 ± 0.00 | 0.13 ± 0.00 | 1.00 ± 0.00 | 1.50 ± 0.00 | 1.50 ± 0.00 | >3.00 ± 0.00 | >3.00 ± 0.00 | 3.13 ± 0.00 | 12.50 ± 0.00 | 125.00 ± 0.00 | 125.00 ± 0.00 |
| M 16 | 0.47 ± 0.00 | 0.94 ± 0.00 | 0.25 ± 0.00 | 1.00 ± 0.00 | 1.50 ± 0.00 | 1.50 ± 0.00 | >3.00 ± 0.00 | >3.00 ± 0.00 | 3.13 ± 0.00 | 12.50 ± 0.00 | 4,000.00 ± 0.00 | 8,000.00 ± 0.00 |
| M 17 | 0.47 ± 0.00 | 0.94 ± 0.00 | 0.13 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.43 | 1.00 ± 0.43 | 0.31 ± 0.11 | 0.75 ± 0.00 | 3.13 ± 0.00 | 12.50 ± 0.00 | 125.00 ± 0.00 | 125.00 ± 0.00 |
| M 18 | 0.47 ± 0.00 | 0.94 ± 0.00 | 0.17 ± 0.07 | 1.00 ± 0.00 | 1.50 ± 0.00 | 1.50 ± 0.00 | 0.19 ± 0.00 | 0.38 ± 0.00 | 3.13 ± 0.00 | 12.50 ± 0.00 | 2,000.00± 0.00 | 8,000.00 ± 0.00 |
| M 19 | 0.47 ± 0.00 | 1.88 ± 0.00 | 0.17 ± 0.07 | 1.00 ± 0.00 | 1.50 ± 0.00 | 1.50 ± 0.00 | >3.00 ± 0.00 | >3.00 ± 0.00 | 1.56 ± 0.00 | 3.13 ± 0.00 | 2,000.00± 0.00 | 8,000.00 ± 0.00 |
| Mean MRSA (n = 19) b | 0.47 ± 0.00 | 1.83 ± 0.79 | 0.16 ± 0.03 | >1.00 ± 0.00 | 1.33 ± 0.34 | 1.42 ± 0.32 | >1.07 ± 1.19 | >1.25 ± 1.09 | 2.22 ± 1.20 | 9.38 ± 3.45 | 2,328.95 ± 1,729.87 | 5,767.54 ± 2,748.78 |