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Time-kill curves of the the combination at 1× MIC concentration of tetrandrine (Tet, upper) and demethyltetrandrine (d-Tet, lower) with CFZ, respectively against MRA 276, a clinical MRSA strains of SCCmec III type. The viable cells counts reduced by 1.25 (CFZ) and 1.58 (Tet) log10CFU/mL (both additivity) 1.15 (CFZ) and 1.36 (d-Tet) log10CFU/mL (both additivity), respectively.
