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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Cancer J. 2018 Nov-Dec;24(6):328–335. doi: 10.1097/PPO.0000000000000344

Table.

Standard and Experimental Fertility Preservation Options for Male and Female AYA Survivors44,45

Sex Procedures Timing
Male Standard of care
• Sperm cryopreservation • 1–2 days before cancer therapy
Experimental
•Gonadal suppression (GnRH
   Analogs)
• Concomitant with cancer therapy
• Testicular tissue
   cryopreservation
• Before cancer therapy
Female Standard of care
• Embryo or oocyte
   cryopreservation
• 2 weeks before cancer therapy;
   possible second opportunity at least
   4–6 months post-treatment
• Fertility-sparing surgery • Concomitant with cancer surgery
• Ovarian transposition • Before abdomino-pelvic radiation
• Ovarian shielding • Concomitant with abdomino-pelvic
   radiation
Experimental
• Gonadal suppression (GnRH
   Analogs)
• During chemotherapy
• Ovarian tissue    cryopreservation • Before cancer therapy