Table 2. Quantitative analysis of pupillometry in acquired isolated third nerve palsy at the initial examination.
| Characteristics | Ischemic (A) | Non-ischemic | Control (D) | P-value | A vs B | A vs C | A vs D | B vs C | B vs D | C vs D | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Inflammatory (B) | Compressive (C) | ||||||||||
| Maximum pupil size (mm) | 4.40±0.82 (2.80, 6.10) |
5.35±0.77 (3.20, 6.50) |
5.12±1.07 (2.90, 7.10) |
5.34±0.82 (3.70, 7.80) |
<0.001† | <0.001 | 0.002 | <0.001 | 0.523 | 1.000 | 0.298 |
| Minimum pupil size (mm) | 3.15±0.68 (2.00, 4.70) |
4.20±0.93 (2.20, 5.80) |
4.58±1.21 (2.30, 7.10) |
3.70±0.69 (2.50, 5.90) |
0.002† | <0.001 | <0.001 | 0.004 | 0.294 | 0.135 | <0.001 |
| Constriction (%) | 28.7±6.4 (14.0, 40.0) |
22.4±8.7 (3.0, 36.0) |
11.1±10.4 (0.0, 29.0) |
30.9±4.2 (24.0,41.0) |
<0.001‡ | 0.007 | <0.001 | 0.355 | <0.001 | <0.001 | <0.001 |
| Latency (sec) | 0.26±0.04 (0.19, 0.34) |
0.26±0.03 (0.22, 0.34) |
0.29±0.24 (0.00, 1.20) |
0.23±0.02 (0.19, 0.28) |
0.721‡ | 0.999 | 0.535 | 0.622 | 0.460 | 0.886 | 0.082 |
| Average constriction velocity (mm/sec) | 2.76±0.70 (1.33, 4.14) |
2.63±0.94 (0.16, 3.94) |
1.25±1.16 (0.00, 3.44) |
3.54±0.48 (2.12, 4.97) |
<0.001‡ | 0.922 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
| Maximum constriction velocity (mm/sec) | 3.73±1.00 (1.85, 5.66) |
3.51±1.11 (1.16, 5.18) |
1.76±1.45 (0.00, 4.29) |
4.65±0.65 (2.77, 6.33) |
<0.001‡ | 0.857 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
| Average dilation velocity (mm/sec) | 0.73±0.23 (0.36, 1.46) |
0.59±0.28 (0.01, 1.06) |
0.39±0.34 (-0.15, 1.08) |
0.88±0.16 (0.50, 1.26) |
<0.001‡ | 0.117 | <0.001 | 0.006 | 0.044 | <0.001 | <0.001 |
† One-way ANOVA for continuous parametric variables.
‡ Kruskal-Wallis test and Mann-Whitney U test for continuous nonparametric variables.
P-values in boldface indicate statistical significance.