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. Author manuscript; available in PMC: 2020 Feb 1.

Published in final edited form as: Mol Imaging Biol. 2019 Feb;21(1):19–24. doi: 10.1007/s11307-018-1215-x

Fig. 2 — Longitudinal course of TB infection. The waterfall plot depicts the longitudinal change in the relative diseased tissue volume between a baseline and the representative weeks (b 16, c 20, and d 28 weeks after infection) as the log₂ fold change (log₂ (week change/baseline)) and the correlation with treatment outcomes: no-D (no drugs), HR (isoniazid + rifampicin), HRZ (isoniazid + rifampicin + pyrazinamide), HZ (isoniazid + pyrazinamide). Subjects taking the same antibiotic cocktail present a similar response (improvement or worsening) with respect to the baseline.

Inline graphic — Longitudinal course of TB infection. The waterfall plot depicts the longitudinal change in the relative diseased tissue volume between a baseline and the representative weeks (b 16, c 20, and d 28 weeks after infection) as the log₂ fold change (log₂ (week change/baseline)) and the correlation with treatment outcomes: no-D (no drugs), HR (isoniazid + rifampicin), HRZ (isoniazid + rifampicin + pyrazinamide), HZ (isoniazid + pyrazinamide). Subjects taking the same antibiotic cocktail present a similar response (improvement or worsening) with respect to the baseline.