Table 5.
Effect of additional A alleles at rs1051730 on child’s autism spectrum disorder and ASD traits
| Pregnancy smokers | Pregnancy non-smokers | |||||
|---|---|---|---|---|---|---|
| Outcome | N | OR [95% CI] | p-Value | N | OR [95% CI] | p-Value |
| Any ASD | 2037 | 0.79 [0.40, 1.56] | 0.504 | 5399 | 1.09 [0.77, 1.53] | 0.628 |
| SCDC score | 1085 | 0.89 [0.66, 1.20] | 0.446 | 3911 | 0.95 [0.78, 1.15] | 0.575 |
| CCC coherence (reverted) | 1002 | 0.87 [0.64, 1.18] | 0.373 | 3923 | 0.80 [0.68, 0.95] | 0.010 |
| Repetitive behaviour | 1197 | 0.81 [0.59, 1.11] | 0.197 | 4152 | 0.90 [0.74, 1.09] | 0.277 |
| EAS sociability (reverted) | 1417 | 1.07 [0.84, 1.37] | 0.572 | 4659 | 1.04 [0.91, 1.19] | 0.563 |
| N | Beta [95% CI] | p -Value | N | Beta [95% CI] | p -Value | |
| ASD factor mean score (standardised) |
1876 | 0.03 [−0.03, 0.10] | 0.345 | 5316 | 0.00 [−0.04, 0.04] | 0.998 |
ASD autism spectrum disorder, SCDC Social and Communication Disorders Checklist, CCC Children’s Communication Checklist, EAS Emotionality Activity and Sociability