Table 2.

The association between denosumab use and breast cancer risk

Strata	BC events		Univariate
	No denosumab	Denosumab	HR (95% CI)	P
Ever/never denosumab use	957	281	0.87 (0.76–1.00)	0.04
Cumulative dose
Per injection			0.98 (0.94–1.01)	0.15a
1–2 injections	-	124	0.82 (0.68–1.00)	0.04
3–4 injections	-	71	0.88 (0.69–1.13)	0.32
5+injections	-	86	0.95 (0.75–1.20)	0.65

^aP – Trend