Table 1.
Inhibitors and their relative targets.
| Name | Target | Final concentration | Manufacturer |
|---|---|---|---|
| Chloroquinin | Cytoplasmic TLR (7/9/21) | 100 μM | InvivoGen |
| 2-aminopurine | TLR4/9/21 and PKR | 5 mM | InvivoGen |
| OxPAPC | TLR2/4 | 50 μM | InvivoGen |
| Polymyxin B | TLR4 | 100 μM | InvivoGen |
| Anti-mTLR2-IgG | TLR2 | 0.66 nM | InvivoGen |
| YM201636 | TLR9 | 5 μM | InvivoGen |
| Gefitinib | NOD (RIP2) | 20 μM | InvivoGen |
| Piceatannol | Dectin | 10 μM | InvivoGen |
| Glybenclamide | NLRP3 | 50 μM | InvivoGen |
| Parthenolide | NLRP1/3 | 40 μM | InvivoGen |
| Wortmannin | PI3K | 40 nM | Sigma |
| Gö 6983 | PKC | 100 nM | Sigma |
| D609 | PLC | 100 μM | Sigma |
| SB203580 | p38MAPK | 40 μM | InvivoGen |
| SP600125 | JNK | 50 μM | InvivoGen |
| PD98059 | ERK | 200 μM | InvivoGen |
| Celastrol | NF-KB | 10 μM | InvivoGen |