Table 3.
Multivariable-adjusted regression analysis of the correlation between serum netrin-1 levels and IFG or type 2 diabetes (n = 218).
| Model 1 | Model 2 | Model 3 | ||||
|---|---|---|---|---|---|---|
| R2 | 0.326 | R2 | 0.405 | R2 | 0.425 | |
| STD β | P-value | STD β | P-value | STD β | P-value | |
| IFG or Type 2 Diabetes | 0.266 | < 0.001 | 0.293 | < 0.001 | 0.251 | 0.008 |
| Sex | −0.209 | 0.001 | −1.654 | 0.100 | −0.136 | 0.114 |
| Age | 0.394 | < 0.001 | 0.264 | 0.002 | 0.347 | 0.001 |
| BMI | −0.028 | 0.654 | 0.005 | 0.949 | −0.044 | 0.629 |
| HbA1c | – | – | −0.006 | 0.938 | −0.055 | 0.523 |
| ALT | – | – | −0.028 | 0.715 | −0.079 | 0.351 |
| HDL cholesterol | – | – | −0.149 | 0.034 | −0.103 | 0.176 |
| statin user | – | – | 0.061 | 0.338 | 0.032 | 0.642 |
| eGFR | – | – | −0.165 | 0.063 | −0.113 | 0.261 |
| HOMA-IR | – | – | – | – | 0.223 | 0.026 |
Log-transformation was used for variables (HbA1c, ALT, HDL cholesterol, eGFR, and HOMA-IR).
ALT, alanine aminotransferase; BMI, body mass index; eGFR, estimated glomerular filtration rate; HDL, high density lipoprotein; HOMA-IR, Homeostasis model assessment of insulin resistance; LDL, low density lipoprotein; STD, standardized.