Figure 4. The effect of cross‐strain fostering on the clock gene expression in the colon of pups.

Daily Per1, Per2, Nr1d1 and Bmal1 expression profiles were detected in 10‐day‐old (A) and 30‐day‐old (B) Wistar rat or SHR pups reared by their genetic mothers as control (full circles, full lines) or exposed to cross‐strain fostering (full triangles, dashed lines). The pups were sacrificed in 4‐h intervals over 24 h. Time is expressed as circadian time (CT); CT0 represents the time of lights on in the previous LD12:12 cycle. The data are expressed as the mean ± SEM, n = 3−5/time point. For statistical comparisons, see Table 3.