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These are mainly ATP‐binding cassette (ABC) transporters. Some, e.g. P‐glycoprotein (PGP; ABCB1), reduce entry into cells. Others, e.g. multidrug resistance protein (MRPs; ABCCs), ligand (drug or toxin) combines with glutathione, glucuronic acid or sulphate in cells before efflux. BCRP, breast cancer resistance protein (ABCG2). ‘Others’ include SLC efflux (SLCO) transporters.
