Table 4.

Expression profiles of end‐of‐pathway genes comparing MO and CON fetal livers at 0.9G

Pathway, direction, z‐score)	End of pathway genes	Direction of change	Downstream pathway
Wnt signalling, up, 2.7	Peroxisome proliferator activated receptor delta, PPARδ	Up	Cell cycle
Tricarboxylic acid cycle, down, 7.2	Dihydrolipoamide S‐succinyltransferase, DLD	Down	NADH
	Dihydrolipoamide dehydrogenase, DLST	Down
	Succinate‐CoA ligase ADP‐forming β‐subunit, SUCLA2 Oxoglutarate dehydrogenase, OGDH	Down
Proteasome, down, 4.7	Proteasome 26S subunit ATPase 5, PSMC5	Down	Protein degradation
	Proteasome 26S subunit ATPase 1, PSMC1	Down
	Proteasome 26S subunit non‐ATPase 6, PSMD6 Thimet oligopeptidase 1, THOP1	Down
Oxidative phosphorylation, down, 3.5	NADH: ubiquinone oxidoreductase subunit B3, NDUFB3	Down	Mitochondrial complex I
	NADH: ubiquinone oxidoreductase core subunit B2, NDUFB2	Down
	Succinate dehydrogenase complex flavoprotein subunit A, SDHA	Down	Mitochondrial complex II
	Cytochrome c oxidase subunit 6B2, COX6B2	Down	Mitochondrial complex IV
	ATP synthase, ATP5L	Down	Mitochondrial complex V
Glycolysis, down, 2.7	Pyruvate dehydrogenase (lipoamide) alpha 1, PDHA1	Down	Amino acid biosynthesis
	Pyruvate kinase, PKLR	Down	Pyruvate