Nonnull-distribution parameters and their corresponding estimates for the nonequivalence test for the factorial design. Models M1 and M3 each have an approximate noncentral nonnull distribution with noncentrality parameter and degrees of freedom and . Model M2 has an approximate noncentral, chi-squared nonull distribution with noncentrality parameter , and degrees of freedom . Notes: = effect size as defined by Eq. (26); = number of tests, with ; = number of readers; = number of cases in the pilot study from which parameter estimates were computed, or the number of cases corresponding to the error variance if parameter values are conjectured; = number of cases in planned study; , , , , and , are OR estimates from a factorial-design pilot study with cases, or are conjectured values; NA = not applicable.