Table 2. Stratified analyses of three KLK3 polymorphisms on prostate cancer risk.

			R-allele vs. W-allele			WR vs. WW			RR vs. WW			RR+WR vs. WW			RR vs. WR+WW
Variables	N	Case/Control	OR (95%CI)	Pheter*	P	OR (95%CI)	Pheter*	P	OR (95%CI)	Pheter*	P	OR (95%CI)	Pheter*	P	OR (95%CI)	Pheter*	P
rs2735839	4	5394/5389	0.93 (0.63–1.39)	<0.001	0.736	0.98 (0.59–1.64)	<0.001	0.947	0.85 (0.40–1.82)	<0.001	0.678	0.97 (0.58–1.61)	<0.001	0.906	0.81 (0.48–1.34)	<0.001	0.407
Ethnicity
Asian	2	393/522	1.24 (0.63–2.44)	0.001	0.526	1.47 (0.23–9.20)	<0.001	0.682	1.50 (0.32–7.14)	<0.001	0.609	1.50 (0.26–8.56)	<0.001	0.647	1.11 (0.83–1.49)	0.418	0.469
Caucasian	2	5001/4867	0.72 (0.42–1.24)	<0.001	0.236	0.75 (0.45–1.25)	<0.001	0.267	0.53 (0.17–1.67)	<0.001	0.276	0.72 (0.41–1.26)	<0.001	0.248	0.57 (0.21–1.56)	<0.001	0.274
rs266882	3	1614/1981	0.87 (0.67–1.12)	0.003	0.276	0.95 (0.81–1.12)	0.240	0.533	0.75 (0.45–1.26)	0.002	0.274	0.86 (0.65–1.15)	0.062	0.305	0.81 (0.53–1.25)	0.002	0.347
Source of control
PB	2	1175/1502	0.79 (0.48–1.29)	0.001	0.349	1.00 (0.83–1.21)	0.170	0.981	0.61 (0.22–1.71)	0.001	0.352	0.81 (0.46–1.41)	0.060	0.456	0.66 (0.30–1.46)	0.001	0.310
rs1058205	5	28830/28999	0.75 (0.64–0.88)	<0.001	<0.001	0.78 (0.65–0.93)	<0.001	0.007	0.58 (0.42–0.81)	<0.001	0.001	0.74 (0.62–0.88)	<0.001	0.001	0.63 (0.48–0.82)	<0.001	0.001
Ethnicity/source of control
Caucasian/PB	4	28562/28701	0.77 (0.65–0.91)	<0.001	0.002	0.80 (0.66–0.98)	<0.001	0.027	0.58 (0.41-0.82)	<0.001	0.002	0.76 (0.63–0.92)	<0.001	0.005	0.63 (0.47–0.83)	<0.001	0.001

*P value of Q-test for heterogeneity test (P_heter)