Table 1.

Patient characteristics

Demographic/characteristic	Total patients (N = 51)
Sex, n (%)
Female	22 (43)
Male	29 (57)
Age, median (range), y	50.0 (19-81)
Disease at study entry, n (%)
AML (n = 43)
MLL-r	33 (65)
MLL-PTD	2 (4)
MLL-r and MLL-PTD	2 (4)
MLL-wt	6 (12)
ALL (n = 6)
MLL-r	4 (8)
MLL-wt	2 (4)
MLL (n = 1)
MLL-PTD	1 (2)
CMML (n = 1)
MLL-wt	1 (2)
Prior systemic therapy regimens, n (%)
1	2 (4)
2	11 (22)
≥3	38 (75)
Prior allogeneic hematopoietic cell transplants, n (%)
1	19 (37)
2	1 (2)

MLL-r and MLL-PTD were identified locally through standard karyotyping or 11q23 FISH (MLL-r) or NGS- or PCR-based methods (MLL-PTD). MLL-wt = no MLL rearrangement detected.