Table 1.
RSV Metabolites (µM) | 50 mg/Kg | 100 mg/Kg | 200 mg/Kg | |
---|---|---|---|---|
Phase II | R4G | 18.52 ± 4.54 | 15.45 ± 1.69 | 20.53 ± 7.73 |
R3G | 12.44 ± 4.85 | 8.43 ± 3.79 | 1.84 ± 0.61 * | |
RDG | 0.19 ± 0.04 | 0.29 ± 0.09 | 0.23 ± 0.04 | |
R4S | 0.12 ± 0.02 | 0.16 ± 0.05 | 0.27 ± 0.09 | |
R3S | 7.06 ± 2.66 | 5.69 ± 1.21 | 5.59 ± 2.04 | |
RDS | 0.80 ± 0.31 | 1.39 ± 0.31 | 0.66 ± 0.09 | |
RSG | 0.83 ± 0.15 | 1.00 ± 0.14 | 0.83 ± 0.21 | |
Microbiota | DRG | 3.95 ± 0.60 | 2.72 ± 0.66 | 9.43 ± 2.28 * |
DRS | 1.15 ± 0.46 | 1.24 ± 0.63 | 3.92 ± 1.30 | |
DRSG | 0.11 ± 0.02 | 0.15 ± 0.04 | 0.21 ± 0.06 |
Abbreviations: R4G: resveratrol-4′-glucuronide; R3G: resveratrol-3-glucuronide; R3S: resveratrol-3-sulfate; R4S: resveratrol-4′-sulfate; RDS: resveratrol-disulfate; RDG: resveratrol-diglucoronide; RSG: resveratrol-sulfate-glucuronide; DRG: dihydroresveratrol-glucuronide; DRS: dihydroresveratrol-sulfate; DRSG: dihydroresveratrol-sulfate-glucuronide. * p < 0.05.