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. 2018 Nov 9;10(11):465. doi: 10.3390/toxins10110465

Table 5.

Kidney, lung and plasma antioxidant and oxidation product data of the rats (GSH: reduced glutathione, GSHPx: glutathione peroxidase, CD: conjugated dienes, CT: conjugated trienes, MDA: malondialdehyde).

Kidney Days in Treatment Control 20 ppm 50 ppm 100 ppm
GSH (micromol/g) 5 2.65 ± 0.44 a 4.26 ± 1.09 ab 6.65 ± 0.79 ab 5.24 ± 1.00 b
10 3.19 ± 0.47 a 4.68 ± 0.21 b 4.86 ± 0.46 b 5.3 ± 0.61 b
GSHPx (IU/g prot.) 5 2.47 ± 0.38 ab 1.99 ± 0.86 a 3.13 ± 0.4 b 2.5 ± 0.33 ab
10 2.11 ± 0.1 a 2.89 ± 0.35 b 2.82 ± 0.18 b 2.97 ± 0.51 b
MDA (nmol/g) 5 52.2 ± 8.0 ab 57.7 ± 5.09 b 44.3 ± 2.89 a 63.4 ± 10.1 b
10 66.5 ± 11.3 b 55.0 ± 8.27 ab 41.9 ± 6.24 a 54.8 ± 9.75 ab
Lung Days in Treatment Control 20 ppm 50 ppm 100 ppm
GSH (micromol/g) 5 3.44 ± 0.39 3.81 ± 0.54 3.4 ± 0.37 3.41 ± 0.33
10 3.49 ± 0.45 3.75 ± 0.47 2.94 ± 0.44 3.26 ± 0.58
GSHPx (IU/g prot.) 5 2.97 ± 0.42 3.26 ± 0.68 3.16 ± 0.48 3.06 ± 0.36
10 2.69 ± 0.29 2.97 ± 0.63 2.56 ± 0.27 2.67 ± 0.48
MDA (nmol/g) 5 28.6 ± 6.54 ab 35.2 ± 6.67 b 24.1 ± 3.16 a 27.7 ± 4.28 ab
10 35.3 ± 4.91 a 55.6 ± 5.03 c 39.1 ± 2.78 ab 42.9 ± 4.25 b
Plasma Days in Treatment Control 20 ppm 50 ppm 100 ppm
GSH (micromol/g) 5 3.34 ± 0.29 ab 3.44 ± 0.34 b 2.8 ± 0.34 a 3.45 ± 0.38 b
10 3.16 ± 0.25 a 3.46 ± 0.29 ab 3.32 ± 0.23 ab 3.97 ± 0.83 b
GSHPx (IU/g prot.) 5 3.02 ± 0.35 b 2.47 ± 0.17 a 2.47 ± 0.36 a 2.57 ± 0.33 ab
10 2.69 ± 0.25 2.73 ± 0.19 2.83 ± 0.29 2.58 ± 0.34
MDA (nmol/g) 5 12.4 ± 1.43 a 14.1 ± 1.46 ab 14.5 ± 1.3 ab 15.3 ± 1.24 b
10 12.4 ± 0.91 a 14.5 ± 1.63 b 12.4 ± 0.6 a 16.7 ± 1.11 c

a, b: small uppercase letters indicate significant difference (p < 0.05) between means of one row. Bold number pairs indicate significant difference (p < 0.05) between 5- and 10-day treatment data.