3D structures of representative toxins belonging to each clinically relevant toxin family. (a) Snake toxins. (b) Scorpion toxins. (c) Spider toxins. 3FTx, three-finger toxin; PLA2, phospholipase A2; SVMP, snake venom metalloproteinase; SVSP, snake venom serine proteinase; DTx, dendrotoxin; BaP1, Bothrops asper P-I-type metalloproteinase; AaV-SP-I, Agkistrodon actus serine proteinase I; AahII, Androctonus australis hector toxin II; Cn2, Centruroides noxius Hoffmann toxin 2; Smase I, Loxosceles laeta sphingomyelinase I; PDB ID, Protein Data Bank accession ID. Images were created using PyMOL (The PyMOL Molecular Graphics System, Version 2.2 Schrödinger, LLC).