Figure 4.
Effects of poecistasin on FeCl3-induced carotid artery injury model. Different concentrations of recombinant poecistasin (0.2, 5 and 10 mg/kg) and heparin sodium (20 mg/kg) were injected by tail vein 10 min before surgery. After treatment with 10% FeCl3, blood flow at region of interest (ROI, indicated by red box) was monitored for 0, 5, 10, 15, 20, 25 and 30 min, respectively. Representative images of carotid artery blood flow (A) by the laser speckle perfusion imaging and quantification of carotid artery blood flow (B) by measuring the perfusion unit of ROI are shown. NC: saline. Data represent mean ± SD (n = 6).