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. 2018 Nov 13;10(11):625. doi: 10.3390/v10110625

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The p24 capsid domain (p24CA) levels in the supernatant collected from SupT1 cells harbouring Ank^GAG1D4 and Ank^A32D3 after infection with 131 Gag/PR chimeric viruses. (A) Distribution of p24CA showed that the mean ± SEM of SupT1/Ank^A32D3 and SupT1/Ank^GAG1D4 was 186.5 ± 25.8 µg/mL and 62.2 ± 16.0 µg/mL, respectively. (B) Significant reduction of p24CA in SupT1/Ank^GAG1D4 compared with SupT1/Ank^A32D3 by individual samples. ** p < 0.01 was determined using a two-tailed paired Student t-test. The percentage of samples that experience reduction was 98.47%.