Figure 2.

Cell-specific steroid signaling in MDD patients and matched healthy controls. Steroid-related gene expression (mean ± S.E.M) in purified (A) monocytes and (B) T cells in MDD patients compared to matched healthy controls. GR, Glucocorticoid Receptor; MR, Mineralocorticoid Receptor; 11β-HSD1, 11β-Hydroxysteroid Dehydrogenase Type 1; GILZ, Glucocorticoid-Induced Leucine Zipper Gene; HC, Healthy Controls; MDD, Major Depressive Disorder. Gene expression is depicted as fold change relative to housekeeping genes.