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. 2018 Oct 31;10(11):599. doi: 10.3390/v10110599

Figure 1.

Figure 1

Epstein–Barr virus (EBV)-encoded proteins involved, or likely involved, in the positive or negative regulations of the first (LMP1, LMP2A, EBNA3C, RTA, BHRF1, and BALF1) or the last (unknown) autophagic steps. The inhibition of the first steps of autophagy by EBV has been found during de novo infection of immune cells, whereas the inhibition of the last degradative phases has been found mainly during the viral reactivation from latency.