Table 4.

Expression of CCND1b mRNA and cyclin D1b protein in an independent cohort of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) and invasive encapsulated follicular variant of papillary thyroid carcinoma.

Molecular Alteration	NIFTP (n = 34)	Invasive Encapsulated Follicular Variant of Papillary Thyroid Carcinoma (n = 24)	p-Value
High expression of CCND1b mRNA	18 (52.9%)	13 (54.2%)	0.927
High expression of nuclear cyclin D1b	5 (14.7%)	9 (37.5%)	0.046
High expression of cytoplasmic cyclin D1b	4 (11.8%)	7 (29.2%)	0.096
BRAF V600E mutation	0	0
BRAF K601E mutation	2 (5.9%)	0	0.339
RAS mutation (total)	20 (58.8%)	13 (54.2%)	0.724
NRAS mutation	14 (41.2%)	8 (33.3%)	0.544
HRAS mutation	6 (17.6%)	4 (16.7%)	0.605
KRAS mutation	0	2 (8.3%)	0.167