Table 1.
Dimensions and encapsulation efficiency (EE%) (mean ± SD; n = 4) of the samples prepared according to the 23 full factorial experimental design taking into account, as factors, the chitosan (CS) concentration 0.1–0.2% (w/v), the stoichiometric ratio chitosan: oleic acid (CS-OA) (1:0.2–1:1), and the ULTRA-TURRAX stirring speed (13,500–24,000 rpm).
| Independent Variables (Factors) | Dependent Variables (Responses) | |||
|---|---|---|---|---|
| CS Conc (% w/v) | CS-OA Ratio | Stirring Rate (rpm) | Dimensions nm (±SD) | EE% (±SD) |
| −1 | −1 | −1 | 1829 (±303) | 70.83 (±1.31) |
| 1 | −1 | −1 | 610 (±47) | 80.92 (±0.06) |
| −1 | 1 | −1 | 627 (±16) | 85.42 (±1.72) |
| 1 | 1 | −1 | 591 (±26) | 89.58 (±0.09) |
| −1 | −1 | 1 | 1186 (±197) | 68.35 (±7.37) |
| 1 | −1 | 1 | 832 (±93) | 79.39 (±2.54) |
| −1 | 1 | 1 | 634 (±19) | 72.19 (±5.60) |
| 1 | 1 | 1 | 620 (±24) | 86.51 (±1.33) |
| 0 | 0 | 0 | 760 (±23) | 71.28 (±0.80) |
| 0 | 0 | 0 | 759 (±17) | 72.68 (±2.04) |
| 0 | 0 | 0 | 733 (±32) | 76.62 (±1.36) |