Table 4.
Comparison of OXT and clinical parameters in our study to the literature.
| Clinical parameter | Yuan and colleagues’ findings20 |
Our study findings |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| MetS group N = 75 | non-MetS N = 95 | p value | Control group N = 30 | MetS group N = 30 |
MetS pre/T2DM group N = 29 | P1a | P2a | P3a | |
| Age (years) | 47.8 ± 11.3 | 46.7 ± 9.4 | 0.517 | 28 (22.5–30.5) | 46 (37.8–54.3) | 52 (43.5–55) | <0.001 | <0.001 | 0.081 |
| Gender, male (%) | 60.0 | 71.5 | 0.112 | 8 (26.7) | 11 (36.7) | 15 (51.7) | 0.136 | ||
| BMI (kg/m2) | 26.8 ± 3.2 | 23.6 ± 2.7 | <0.001 | 22.21 (19.9–24.5) |
31.2 (27.2–35.8) |
31.8 (27.5–35.2) |
<0.001 | <0.001 | 0.705 |
| WC (cm) | 93.2 ± 8.3 | 82.9 ± 8.8 | <0.001 | 0.82 (0.8–0.9) | 0.91 (0.88–0.93) | 0.9 (0.87–0.92) | <0.001 | 0.006 | 0.144 |
| SBP (mmHg) | 130.8 ± 15.5 | 123.0 ± 12.0 | <0.001 | 125 (121.3–128.8) | 135 (130–140) | 145 (140–155) | <0.001 | <0.001 | 0.065 |
| DBP (mmHg) | 81.4 ± 9.4 | 77.7 ± 9.5 | 0.013 | 75 (70–80) | 84 (76.5–85.5) | 85 (77.5–90) | <0.001 | <0.001 | 0.634 |
| HbA1C (%) | 8.1 ± 2.4 | 6.7 ± 2.5 | <0.001 | 5.25 (5.1–5.4) | 5.4 (5.2–5.5) | 5.9 (5.7–6.8) | 0.072 | <0.001 | <0.001 |
| FPG (mg/dl) | 151.9 ± 57.6 | 124.5 ± 58.7 | 0.003 | 87 (79.5–90) | 86 (79.8–93.3) | 112 (103–118.3) | 0.706 | <0.001 | <0.001 |
| TC (mg/dl) | 90.3 ± 20 | 82.7 ± 17.4 | 0.010 | 169 (131.3–209.8) | 207 (163.5–230.5) | 187.9 (158.9–254) | 0.025 | 0.058 | 0.755 |
| TG (mg/dl) | 50.6 ± 30.3 | 25.4 ± 14.4 | <0.001 | 72 (49.3–94.3) | 199 (156.3–262) | 179.5 (127.7–242.5) | <0.001 | <0.001 | 0.308 |
| LDL-C (mg/dl) | 55.5 ± 17.8 | 52.1 ± 15.5 | 0.206 | 88 (74.3–119) | 111.5 (84.5–155.0) | 130.5 (101.7–174.3) | 0.026 | <0.001 | 0.228 |
| HDL-C (mg/dl) | 19.1 ± 4.1 | 24.1 ± 7.2 | <0.001 | 50 (44–70.5) | 38 (34.5–40) | 38.4 (34.6–42) | <0.001 | <0.001 | 0.571 |
| OXT (pg/ml) | 8000 (6670–9490) | 9070 (8080–10370) | <0.001 | 4176.6 (2407.1–5243.3) | 1975.4 (1522.3–3191.2) | 1403 (1034.0–2567.3) | 0.009 | 0.001 | 0.071 |
P1 = Control group compared to MetS group. P2 = Control group compared to MetS pre/T2DM group. P3 = MetS group compared to MetS pre/T2DM group.
BMI, body mass index; DBP, diastolic blood pressure; FBG, fasting blood glucose; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; OXT, oxytocin; SBP, systolic blood pressure; TC: total cholesterol; TG, triglyceride; WC, waist circumference.