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. 2018 Sep 12;42(11):1556–1561. doi: 10.1097/PAS.0000000000001148

FIGURE 1.

FIGURE 1

Cancerization of ducts, or intraductal spread of invasive ductal adenocarcinoma, showing overexpression of p53 (B), lack of expression of p53 (D) and loss of Smad4 (F). H&E stain (A, C, E). p53 immunostain (B, D). Smad4 immunostain (E).