Table 2.
Hazard ratio (HR) and 95% CI of death and lung cancer death and recurrencea
| Analysis by the multivariate Cox proportional hazards model | Low VASH1 | Medium VASH1 | High VASH1 |
|---|---|---|---|
| All Periods | |||
| Person‐years | 104.9 | 110.7 | 144.3 |
| Death and recurrence rate (per 100 person‐years) | 16.2 | 12.7 | 5.5 |
| Crude HR (95% CI) | Ref | 0.84 (0.41‐1.71) | 0.38 (0.16‐0.87) |
| Multivariate adjusted HR (95% CI) | Ref | 0.83 (0.37‐1.88) | 0.42 (0.17‐0.99) |
| First 3 y After the Operation | |||
| Person‐years | 59.4 | 56.8 | 70.1 |
| Death and recurrence rate (per 100 person‐years) | 20.2 | 21.1 | 7.1 |
| Crude HR (95% CI) | Ref | 1.06 (0.48‐2.36) | 0.36 (0.13‐1.01) |
| Multivariate adjusted HR (95% CI) | Ref | 1.16 (0.46‐2.96) | 0.40 (0.14‐1.17) |
| More Than 3 y After the Operation | |||
| Person‐years | 45.5 | 53.9 | 74.2 |
| Death and recurrence rate (per 100 person‐years) | 11.0 | 3.7 | 4.0 |
| Crude HR (95% CI) | Ref | 0.36 (0.070‐1.88) | 0.39 (0.093‐1.63) |
| Multivariate adjusted HR (95% CI) | Ref | 0.20 (0.026‐1.60) | 0.28 (0.052‐1.49) |
Abbreviation: VASH1, vasohibin‐1.
a
Multivariate HR (95% CI) has been adjusted for age, sex, baseline performance status (0, 1, or more), and pathological stage (stages IA, IB, and IIA/IIB/IIIA).