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Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway associated with HIF-1α responsive genes. Through bioinformatics analysis, multiple pathways of HIF-1α differentially binding target genes and HIF-1α coregulated genes were obtained in mice bone marrow (BM) cells compared with the control group. The HIF-1α target genes, which correspond to the reduced enrichment peak in the 150 mg/kg (LB) group, were significantly enriched in the KEGG signaling pathway.
