Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 14;10(11):473. doi: 10.3390/toxins10110473

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The predicted toxins were aligned by MUSCLE and sorted by pairwise alignment to close matching protein. (A) The RelE toxins MW2329, MW2380, and MW1230 were shorter in length and showed homology towards YefM-YoeB sub-family, while the MW0324 and MW1394 were longer in length and displayed less conservation, possibly making a new sub-family. (B) The GNATs toxins showed a functional site of 28 residues (41–68 aa) that contained the most conserved region in this family. (C) A moderate consensus site of 20 residues (30–49 aa) was detected in the nuclease family. The nuclease toxins MW1311, MW1403, and MW1733 were closely related in sequence alignment, while MW0461 was less conserved.

The predicted toxins were aligned by MUSCLE and sorted by pairwise alignment to close matching protein. (A) The RelE toxins MW2329, MW2380, and MW1230 were shorter in length and showed homology towards YefM-YoeB sub-family, while the MW0324 and MW1394 were longer in length and displayed less conservation, possibly making a new sub-family. (B) The GNATs toxins showed a functional site of 28 residues (41–68 aa) that contained the most conserved region in this family. (C) A moderate consensus site of 20 residues (30–49 aa) was detected in the nuclease family. The nuclease toxins MW1311, MW1403, and MW1733 were closely related in sequence alignment, while MW0461 was less conserved.