Table A2.

Patients with stage I to III lung cancer harboring rare EGFR mutation.

Patient No.	Age	Sex	Smoking	Initial Stage	TTF-1	EGFR Mutation		TKI Treatment
						Exon	Mutation	Medication	Line of Treatment	Initial Response
1	68	Female	never	IA	+	exon 21	L861Q	Gefitinib	1st line	PR
2	60	Female	never	IA	+	exon 21	L861Q	Afatinib	1st line	SD
3	42	Male	20 pack-year	IIA	+	exon 18	G719X	Afatinib	1st line	PD
4	72	Male	never	IIIA	+	exon 20	S768I	Erlotinib	2nd line	SD
5	53	Female	never	IIIB	+	exon 18	G724S	Gefitinib	2nd line	PR

Abbreviation: ECOG = Eastern Cooperative Oncology Group; TTF-1 = thyroid transcription factor 1, TTF-1 was often used to confirmed the diagnosis of lung adenocarcinoma.