Table 2.

Poxviruses studied in canine tumors.

Family	Genus	Species	Virus	Tumor Type Studied	References
Poxviridae	Leporipoxvirus	Myxoma virus	MYXV wild-type	In vitro in osteosarcoma, transitional cell carcinoma, hemangiosarcoma, mastocytoma, soft tissue sarcoma, stromal gastrointestinal tumor, perianal adenoma, mixed mammary tumor, and renal carcinoma	[136]
			MYXVΔserp1
	Avipoxvirus	Canarypox virus	ALVAC	Canine spontaneous melanoma	[137]
	Ortopoxvirus	Vaccinia Virus	GLV-1h68	Canine mammary adenoma and carcinoma, both in vitro and in vivo in mice	[138,139]
			LIVP1.1.1	Soft tissue sarcoma in vitro and in vivo in mice	[140]
			GLV-1h109	Soft tissue sarcoma in vitro and in vivo in mice, and in vitro in prostatic carcinoma	[141]
			LIVP6.1.1	Soft tissue sarcoma and prostatic carcinoma, both in vitro and in vivo in mice, and in vitro in melanoma and osteosarcoma	[142]
			GLV-5b451	In vitro in mammary carcinoma, mammary adenoma, and prostatic carcinoma, as well as in soft tissue sarcoma in vitro and in vivo in mice	[143]
			NYVAC	Canine spontaneous melanoma	[137]