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. 2018 Nov 2;10(11):420. doi: 10.3390/cancers10110420

Table 2.

General planning-aims for the three external centers. *: Center A constraints for organs-at-risk (OARs) are on OARminusPTV delineations. We report dosimetric results based on entire OAR structures.

PTVs Center A * Center B Center C
D95% ≥100% ≥95%
V95% ≥99%
Dmax ≤110% ≤115%
D99% ≥93% ≥90%
D2% ≤107%
D5% ≤105%
Max Dose (Gy)
Spinal Cord ≤45 ≤45 ≤41
Spinal Cord PRV ≤50
Brainstem ≤54 ≤54 ≤62
Brain ALARA ≤65
Optic Nerve ≤54 ≤54 ≤60
Chiasm ≤54 ≤54 ≤60
Esophagus ≤71.4
Larynx ≤71.4
TMJoint ≤70
Trachea ≤71.4
Eye ≤50
Mandible-PTV ≤70
Mean Dose (Gy)
Parotid <26 <26 <24
Submandibular <30 <26
Oral Cavity <20 <30 <45 (<35 if distal to target)
Pharynx <50 <45
Larynx <20 <30
Esophagus <20 <30 <40 if not in PTV
Middle Ears <30 <30
Eye <35 ALARA <35
Glottis <45 (<20 if distal to target)
Trachea <40