Table 4.

Zones of Inhibition (ZOI) data with EUCAST clinical breakpoint tables v 6.0 and CLSI M100 breakpoints.

Antibiotic Conc. per 10cc Pack SRCS	Species	Zone Diameter (mm)	EUCAST/ CLSI M100	Zone Diameter Breakpoint (mm)		Note
				Susceptible ≥	Resistant ≤
Amikacin 500 mg/2 mL	S. epidermidis (ATCC 12228)	30	EUCAST	22 a	19 a	a Coagulase negative staphylococci
			CLSI	-	-	n/a
	P. aeruginosa (NCTC 13437)	20	EUCAST	18 c	15 c	cPseudomonas spp.
			CLSI	15	12	-
Ceftriaxone 1 g	S. aureus (ATCC 6538)	47	EUCAST	-	-	n/a
			CLSI	-	-	n/a
	S. epidermidis (ATCC 12228)	31	EUCAST	-	-	n/a
			CLSI	-	-	n/a
Cefuroxime 1.5 g	S. aureus (ATCC 6538)	47	EUCAST	-	-	n/a
			CLSI	-	-	n/a
	S. epidermidis (ATCC 12228)	22	EUCAST CLSI	- -	- -	n/a n/a
	P. aeruginosa (NCTC 13437)	28	EUCAST	-	-	n/a
			CLSI	-	-	n/a
	Acinetobacter Baumannii (NCTC 134242)	22	EUCAST CLSI	- -	- -	n/a n/a
Colistamethane Sodium 400 mg	S. aureus (ATCC 6538)	9	EUCAST CLSI	- -	- -	n/a n/a
	S. epidermidis (ATCC 12228)	11	EUCAST CLSI	- -	- -	n/a n/a
	P. aeruginosa (NCTC 13437)	13	EUCAST CLSI	- -	- -	n/a n/a
Ciprofloxacin 1 g	P. aeruginosa (NCTC 13437)	17	EUCAST CLSI	25 c 21	22 c 15	cPseudomonas spp. -
	Acinetobacter Baumannii (NCTC 134242)	15	EUCAST CLSI	21 d 21 d	21 d 15 d	dAcinetobacter spp. d Acinetobacter spp.
Ciprofloxacin 1 g	S. epidermidis (ATCC 12228) S.aureus (NCTC 12493) MRSA (NCTC 134242)	36 25	EUCAST CLSI EUCAST CLSI	20 b 21 b 20 b 21 b	20 b 15 b 20 b 15 b	bStaphylococcus spp. b Staphylococcus spp. b Staphylococcus spp. b Staphylococcus spp.
Daptomycin 1 g	S. epidermidis (ATCC 12228) E. faecalis * (NCTC 12202) P. acnes (NCTC 737) P. aeruginosa (NCTC 13437)	25 13.5 31 11	EUCAST CLSI EUCAST CLSI	- - - -	- - - -	n/a n/a n/a n/a
			EUCAST CLSI EUCAST CLSI	- - - -	- - - -	n/a n/a n/a n/a
Gentamicin 240 mg	S. aureus (ATCC 6538) S. epidermidis (ATCC 12228)	20 30	EUCAST CLSI EUCAST CLSI	18 15 b 22 a 15 b	18 12 b 22 a 12 b	- b Staphylococcus spp. a Coagulase negative staphylococci b Staphylococcus spp.
Imipenem & Cilastatin 500 mg	S. aureus (ATCC 6538) S. aureus (NCTC 12493) MRSA	58 49	EUCAST CLSI	- -	- -	n/a n/a
			EUCAST CLSI	- -	- -	n/a n/a
	S. epidermidis (ATCC 12228)	60	EUCAST CLSI	- -	- -	n/a n/a
Meropenem 1 g	S. epidermidis (ATCC 12228) S. aureus (NCTC 12493) MRSA	56 37	EUCAST CLSI	- -	- -	n/a n/a
			EUCAST CLSI	- -	- -	n/a n/a
	P. aeruginosa (NCTC 13437) Acinetobacter Baumannii (NCTC 134242)	28 22	EUCAST CLSI	24 c 19	18 c 15	cPseudomonas spp. -
			EUCAST CLSI	21 d 18 d	15 d 14 d	dAcinetobacter spp. d Acinetobacter spp.
Nafcillin 1 g	S. aureus (ATCC 6538)	51	EUCAST CLSI	- 22 b	- 21 b	n/a b Staphylococcus spp. Cefoxitin (Oxicillin surrogate)
	S. epidermidis (ATCC 12228) P. aeruginosa (NCTC 13437)	57 13	EUCAST CLSI	- 22 b	- 21 b	n/a b Staphylococcus spp. Cefoxitin (Oxicillin surrogate)
			EUCAST CLSI	- -	- -	n/a n/a
Rifampicin 600 mg	S. epidermidis (ATCC 12228) S. aureus (NCTC 12493) MRSA	15 11	EUCAST CLSI	- 20 b	- 16 b	n/a b Staphylococcus spp.
			EUCAST CLSI	- 20 b	- 16 b	n/a b Staphylococcus spp.
Teicoplanin 400 mg	S. aureus (ATCC 6538) S. aureus (NCTC 12493) MRSA S. epidermidis (ATCC 12228)	18 26 23	EUCAST CLSI EUCAST	- - -	- - -	n/a n/a n/a
			CLSI EUCAST CLSI	- - -	- - -	n/a n/a n/a
Tobramycin 1.2 g	S. aureus (ATCC 6538) S. epidermidis (ATCC 12228)	19 28	EUCAST CLSI	18 -	18 -	- n/a
			EUCAST CLSI	22 a -	22 a -	a Coagulase negative staphylococci n/a
Vancomycin 1 g	S. aureus (ATCC 6538) S. epidermidis (ATCC 12228) E. faecalis * (NCTC 12201) E.faecalis * (NCTC 12202)	21 23 17–18 12–13	EUCAST CLSI EUCAST CLSI	- - - -	- - - -	n/a n/a n/a n/a
			EUCAST CLSI EUCAST CLSI	12 e 17 e 12 e 17 e	12 e 14 e 12 e 14 e	eEnterococcus spp. e Enterococcus spp. e Enterococcus spp. e Enterococcus spp.

* Denotes Vancomycin Resistant Control Strains. (^a–e) Represent the breakpoints for that particular species.