Table 1.
Phenotypic comparisons between Ad-GFP-infected and Ad-ChREBP-infected mice.
| Ad-GFP | Ad-ChREBP | |
|---|---|---|
| BW (g) | 24.35 ± 1.47 | 22.46 ± 0.66 |
| Liver (%BW) | 6.01 ± 0.31 | 9.80 ± 1.69 |
| WAT (%BW) | 1.38 ± 0.16 | 1.09 ± 0.45 |
| BAT (%BW) | 0.56 ± 0.36 | 0.48 ± 0.10 |
| Food intake (g) | 4.03 ± 0.58 | 3.46 ± 0.56 |
| Plasma glucose (mg/dl) | 110.7 ± 25.5 | 46.7 ± 13.5 * |
| Plasma OHBA (mM) | 1.28 ± 0.15 | 0.61 ± 0.36 * |
| Plasma FFA (mM) | 0.56 ± 0.22 | 1.35 ± 0.65 * |
| Plasma Insulin (ng/mL) | 0.32 ± 0.16 | 0.43 ± 0.25 |
| Plasma total cholesterol (mg/dl) | 76.21 ± 9.23 | 59.36 ± 13.01 * |
| Plasma triglyceride (mg/dl) | 92.94 ± 28.54 | 65.91 ± 25.54 * |
| Liver glycogen (mg/g liver) | 112.6 ± 38.1 | 20.3 ± 3.3 * |
| Liver glucose-6-phosphate (μmoles/g liver) | 0.41 ± 0.06 | 0.19 ± 0.05 * |
| Liver total cholesterol (mg/g liver) | 1.21 ± 0.25 | 1.61 ± 0.45 |
| Liver triglyceride (mg/g liver) | 10.5 ± 3.5 | 73.8 ± 37.9 * |
Abbreviations: BW, body weight; WAT, white adipose tissue; BAT, brown adipose tissue; OHBA, 3-hydroxybutyrate; FFA, free fatty acid. Data represent means ± SD (n = 6 per group). * p < 0.05.