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. Author manuscript; available in PMC: 2019 Apr 15.
Published in final edited form as: Pediatr Res. 2018 Oct 15;84(4):545–551. doi: 10.1038/s41390-018-0095-8

Figure 2. High vector genome biodistribution in bone 2 weeks after infusion.

Figure 2.

1.5 × 1011 vector genome of CBA-GALNS or D8/CBA-GALNS vectors were infused intravenously into 7- to 8-weeks-old Galns-/- mice. Vector genome was quantified in selected tissues after 24 hours, 48 hours and 2 weeks after infusion. Results are reported as the ratio of vector genome/diploid cell to the levels observed in CBA-GALNS infused mice. Vector genome was not detected in mice infused with PBS. The data was presented as geometric mean with error bars. *p<0.05. All data n=3 except, n=6 for 48 hours (CBA-GALNS and D8/CBA-GALNS) and n=2 for 2-weeks (CBA-GALNS).