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. 2018 Nov 30;19(Suppl 15):436. doi: 10.1186/s12859-018-2421-x

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — FOSL1 survival analysis by GBM subtypes. Survival analysis was performed by using Kaplan-Meier method based on the gene expression profiles of GBM RNA-seq data and clinical data provided by TCGA. For each GBM subtype (i.e. Proneural, Neural, Classical, Mensenchymal), patients are split according to a median separation into two groups: low- (magenta curve) and high-expression group (cyan curve) referring to patients with expression levels lower than or greater than the 50^th percentile of the distribution of FOSL1 expression values. Finally, we compare these results, for each subtype, with the survival curves obtained considering all patients of each subtype without the two-groups separation (black curve)