Table 2.
Week 0 | Week 12 | Week 24 | p Values | |
---|---|---|---|---|
Echocardiography | ||||
EF (%) | 62.56 ± 7.47 (63.85) 1 | 66.28 ± 9.78 (68.35) | 65.67 ± 9.63 (66.85) | 0.15 |
FS (%) | 34.20 ± 5.22 (35.45) | 37.07 ± 7.28 (38.98) | 36.59 ± 6.86 (37.60) | 0.19 |
CO (L/min) | 10.77 ± 14.47 (5.83) | 16.36 ± 26.16 (5.72) | 14.62 ± 26.18 (5.62) | 0.73 |
SV (mL) | 159.96 ± 274.25 (72.73) | 176.32 ± 217.88 (84.10) | 144.40 ± 217.56 (55.96) | 0.44 |
HR (beat/min) | 82.15 ± 27.82 (85.00) | 82.6 ± 33.18 (83.75) | 86.50 ± 27.07 (92.00) | 0.93 |
LVOTd (cm) | 1.75 ± 0.78 (1.60) | 1.87 ± 0.61 (1.80) | 1.68 ± 0.63 (1.65) | 0.25 |
EDV (mL) | 133.92 ± 104.69 (107.50) | 132.75 ± 99.49 (109.00) | 135.16 ± 98.41 (99.20) | 0.93 |
ESV (mL) | 53.12 ± 50.17 (38.05) | 48.14 ± 46.70 (33.00) | 51.05 ± 48.42 (41.45) | 0.15 |
LVIDd (cm) | 5.00 ± 1.61 (4.80) | 4.99 ± 1.57 (4.83) | 5.05 ± 1.53 (4.64) | 0.89 |
LVIDs (cm) | 3.32 ± 1.20 (3.10) | 3.17 ± 1.18 (2.92) | 3.25 ± 1.21 (3.22) | 0.22 |
CI (L/(min*m2)) | 8.36 ± 8.61 (5.82) | 12.15 ± 15.74 (5.60) | 10.39 ± 15.71 (5.05) | 0.73 |
MPI | 0.84 ± 0.47 (0.66) | 0.76 ± 0.34 (0.89) | 0.75 ± 0.47 (0.70) | 0.48 |
Hematology | ||||
BNP (pg/mL) | 115.6 ± 152.2 (56.9) | 157.4 ± 212.1 (48.8) | 148.0 ± 217.2 (50.8) | 0.63 |
NT-Pro BNP (pg/mL) | 357.1 ± 451.6 (236.0) | 527.2 ± 703.8 (365.5) | 458.3 ± 694.3 (191.5) | 0.23 |
CK (U/L) | 238.0 ± 344.0 (135.5) | 436.2 ± 772.7 (141.5) | 181.9 ± 105.5 (141.5) | 0.70 |
CK-MB (U/L) | 14.2 ± 6.65 (16.0) | 10.8 ± 6.5 (12.0) | 12.6 ± 8.4 (11.0) | 0.52 |
1 means ± standard deviations (medians). BNP, B-type natriuretic peptide; CI, cardiac index; CK, creatine kinase; CK-MB, creatine kinase-muscle/brain; CO, cardiac output; EDV, end-diastolic volume; EF, ejection fractions; ESV, end-systolic volume; FS, fractional shortening; HR, heart rate; LVIDd, left ventricular internal diameter end-diastole; LVIDs; left ventricular internal diameter end-systole; LVOTd, left ventricular outflow tract diameter; MPI, myocardial performance index; NT-Pro BNP, N-terminal pro B-type natriuretic peptide; SV, stroke volume.