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. 2018 Nov 29;44:145. doi: 10.1186/s13052-018-0575-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The protein-protein interaction (PPI) network constructed for the differentially expressed genes (DEGs). The red circles and green diamonds separately stand for up-regulated genes and down-regulated genes. The bigger nodes have higher connectivity degrees. Different edge colors represent different modules (module 1: black; module 2: yellow; module 3: dark blue; module 4: purple; module 5: light blue)