Table 3.

List of non-retained compounds for stone fruit

Food item	Compound	PhytoHub ID	HMDB ID	Biofluid	Reasons for exclusion	References
Cherry	Cyanidin 3-rutoside, cyanidin 3-O-glucoside, cyanidin-3-glucosylrutinoside	PHUB000504 PHUB000503 PHUB001606	HMDB0031458 HMDB0030684 HMDB0037988	Plasma, urine	Common to many anthocyanin-rich foods; very low concentrations even after acute intake; very transient increase (< 2 h)	[79]
Cherry	6-Sulfatoxymelatonin	PHUB001884	HMDB0041815	Urine	Main metabolite of melatonin; common to all melatonin-rich foods. Also endogenous origin, affected by many factors (age, BMI, smoking…)	[84, 85]
Cherry	5-Hydroxyindoleacetic acid	PHUB001475	HMDB00763	Urine	Main metabolite of serotonin; common to all serotonin-containing foods such as banana, pineapple, and walnut; also endogenous origin	[88]
Plum	Anthocyanins: peonidin 3-glucoside, peonidin 3-rutoside, cyanidin monoglucuronide	PHUB001257; PHUB001296;	HMDB13689	Urine	Present in other berries, drupes, and red wine. Very low concentration and short half-life	[96]
Plum	Hippuric acid	PHUB001174	HMDB00714	Urine	Very common metabolite of polyphenols with many possible origins; not specific	[96]
Plum	Caffeic acid	PHUB000574	HMDB01964	Plasma, urine	Widely distributed in plant foods; not specific	[92]
Plum	5-Hydroxymethyl-2-furoic acid, (5-carboxylic acid-2-furoyl)glycine	PHUB001892 PHUB001894	–	Plasma, urine	Metabolites of 5-hydroxymethylfurfural (HMF), also present in coffee, dried fruit, fruit juices and honey	[93]
Cherry	Hydroxycinnamic acids: caffeic acid, ferulic acid, p-coumaric acid, vanillic acid	PHUB000574 PHUB000608 PHUB000316	HMDB0001964 HMDB0000954 HMDB0000484	Plasma	Widely distributed in plant foods; not specific	[97]

Abbreviations: HMDB ID human metabolome database identification number, http://www.hmdb.ca; PhytoHub ID: http://phytohub.eu/