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. 2018 Nov 29;13:31. doi: 10.1186/s12263-018-0618-2

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Effect of TRF on the expression of micro RNAs during proliferation and differentiation of young and senescent myoblasts. Expression of miR-133b (a, b), miR-206 (c, d) and miR-486 (e, f) in young control myoblasts, TRF-treated young myoblasts, senescent control myoblasts and TRF-treated senescent myoblasts. ^aDenotes p < 0.05 compared to young control, ^bp < 0.05 compared to senescent control and ^cp < 0.05 compared to young TRF-treated myoblasts. Data are presented as relative expression value (REV) normalised to RNU6B expression (mean ± SD, n = 3)