Fig. 3.

Intra-NAc effects of A_2A receptor antagonists KW 6002 (KW; 1–2.5 μg/side), SCH 58261 (SCH; 1–2.5 μg/side), and CGS 21680 (CGS; 1–2.5 ng/side) on cocaine (COC; 0.25 mg/kg/infusion) self-administration in rats. The number of active and inactive lever presses (upper panels) and the number of cocaine infusions (lower panels) are shown as the mean (±SEM). **p < 0.01, ****p < 0.0001 vs vehicle (VEH) (Newman-Keuls test); ^{^^}p < 0.01, ^{^^^^}p < 0.0001 vs (VEH) (Dunnett’s test). N = 6–8 rats/group