Table 4. Comparison of serum cytokine and chemokine levels between SEA and NSEA patients.
| Cytokines | SEA (n = 46) | NSEA (n = 127) | P values |
|---|---|---|---|
| IL-8 (pg/mL) | 39.1 ± 58.0 | 50.7 ± 195.4 | 0.563 |
| IL-33 (pg/mL) | 8.89 ± 32.04 | 30.1 ± 130.6 | 0.873 |
| IL-31 (pg/mL) | 262.9 ± 512.7 | 227.8 ± 801.1 | 0.527 |
| Eotaxin-2 (pg/mL) | 1,763.2 ± 1,149.6 | 1,106.05 ± 877.2 | 0.004 |
| TGF-β1 (ng/mL) | 34.9 ± 15.1 | 26.3 ± 14.9 | 0.026 |
| Periostin (ng/mL) | 75.78 ± 31.7 | 77.7 ± 46.3 | 0.946 |
Values are given as mean ± SD for continuous variables. P values were applied by Mann-Whitney U test.
SEA, severe elderly asthma; NSEA, non-severe elderly asthma; IL, interleukin; TGF-β1, transforming growth factor beta 1; SD, standard deviation.