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. 2018 Nov 1;10(11):600. doi: 10.3390/v10110600

Figure 1.

Figure 1

RNA virus mutational spectrum. As RNA viruses mutate, the sequence space is sampled to find areas of higher fitness. This space is hypothesized to be unstable, so it is best for mutation-prone RNA viruses to exist in flatter areas of this space where decreases in fitness are slight.