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. 2018 Sep 16;473(6):709–717. doi: 10.1007/s00428-018-2450-x

Table 3.

Copy number variations for selected genes in 52 SI-NETs. Genes are listed per alphabetical order

Gene Chromosomal location Gain or loss Total (52) [%]
AKT1 14 Gain 16 [30.8]
APC 5 LOH 2 [3.8]
AURKA 20 Gain 6 [11.5]
BCL2 18 LOH 22 [42.3]
BCL2L2 14 Gain 11 [21.2]
BRAF 7 Gain 9 [17.3]
CDH1 16 LOH 8 [15.4]
CDH19 18 LOH 24 [46.2]
CDKN1B 12 LOH 7 [13.5]
CDKN2A 9 LOH 3 [5.8]
DCC 18 LOH 22 [42.3]
EGFR 7 Gain 4 [7.7]
ERBB2 17 Gain 0 [0]
FBXW7 4 LOH 1 [1.9]
FGFR3 4 Gain 3 [5.8]
FHIT 3 LOH 3 [5.8]
FOS 14 Gain 19 [36.5]
GNAS 20 Gain 5 [9.6]
HRAS 11 LOH 9 [17.3]
KDR 4 Gain 15 [28.8]
KIT 4 Gain 15 [28.8]
MAP2K2 19 Gain 11 [21.2]
MDM2 12 Gain 3 [5.8]
MEN1 11 LOH 7 [13.5]
MET 7 Gain 9 [17.3]
MYC 8 Gain 2 [3.8]
MYCL1 1 Gain 6 [11.5]
PDGFRA 4 Gain 15 [28.8]
PIK3CA 3 Gain 0 [0]
PIK3CD 1 LOH 0 [0]
PTEN 10 LOH 2 [3.8]
RICTOR 5 Gain 2 [3.8]
SDHA 5 Gain 15 [28.8]
SDHB 1 LOH 0 [0]
SDHD 16 LOH 18 [34.6]
SMAD4 18 LOH 15 [28.8]
SMAD5 5 Gain 11 [21.2]
SOX12 20 Gain 7 [13.5]
SRC 20 Gain 13 [25.0]
TP53 17 LOH 0 [0]