Table 3.
Gene | Chromosomal location | Gain or loss | Total (52) | [%] |
---|---|---|---|---|
AKT1 | 14 | Gain | 16 | [30.8] |
APC | 5 | LOH | 2 | [3.8] |
AURKA | 20 | Gain | 6 | [11.5] |
BCL2 | 18 | LOH | 22 | [42.3] |
BCL2L2 | 14 | Gain | 11 | [21.2] |
BRAF | 7 | Gain | 9 | [17.3] |
CDH1 | 16 | LOH | 8 | [15.4] |
CDH19 | 18 | LOH | 24 | [46.2] |
CDKN1B | 12 | LOH | 7 | [13.5] |
CDKN2A | 9 | LOH | 3 | [5.8] |
DCC | 18 | LOH | 22 | [42.3] |
EGFR | 7 | Gain | 4 | [7.7] |
ERBB2 | 17 | Gain | 0 | [0] |
FBXW7 | 4 | LOH | 1 | [1.9] |
FGFR3 | 4 | Gain | 3 | [5.8] |
FHIT | 3 | LOH | 3 | [5.8] |
FOS | 14 | Gain | 19 | [36.5] |
GNAS | 20 | Gain | 5 | [9.6] |
HRAS | 11 | LOH | 9 | [17.3] |
KDR | 4 | Gain | 15 | [28.8] |
KIT | 4 | Gain | 15 | [28.8] |
MAP2K2 | 19 | Gain | 11 | [21.2] |
MDM2 | 12 | Gain | 3 | [5.8] |
MEN1 | 11 | LOH | 7 | [13.5] |
MET | 7 | Gain | 9 | [17.3] |
MYC | 8 | Gain | 2 | [3.8] |
MYCL1 | 1 | Gain | 6 | [11.5] |
PDGFRA | 4 | Gain | 15 | [28.8] |
PIK3CA | 3 | Gain | 0 | [0] |
PIK3CD | 1 | LOH | 0 | [0] |
PTEN | 10 | LOH | 2 | [3.8] |
RICTOR | 5 | Gain | 2 | [3.8] |
SDHA | 5 | Gain | 15 | [28.8] |
SDHB | 1 | LOH | 0 | [0] |
SDHD | 16 | LOH | 18 | [34.6] |
SMAD4 | 18 | LOH | 15 | [28.8] |
SMAD5 | 5 | Gain | 11 | [21.2] |
SOX12 | 20 | Gain | 7 | [13.5] |
SRC | 20 | Gain | 13 | [25.0] |
TP53 | 17 | LOH | 0 | [0] |