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. 2018 Nov 2;16(11):428. doi: 10.3390/md16110428

Figure 6.

Figure 6

Effect of compounds 1–11 on lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF-α) secretion in BV-2 cells. Cells were pre-incubated with vehicle (DMSO, 0.1%) or compounds (A) (1–11, 10 μg/mL) and (B) (1 and 9, 0.6–40 μg/mL) for 1 h before stimulation with 1 μg/mL of LPS for 6 hours. TNF-α production was measured by enzyme-linked immunosorbent assay (ELISA). Data represent mean ± SEM measurements in triplicates. Data were analyzed by a one-way analysis of variance (ANOVA) followed by a Tukey′s multiple comparison test. *** p < 0.001 vs. BK; ### p < 0.001 vs vehicle.