Figure 6.

Transfection with a miR-370-3p mimic decreases TGFβ1-induced growth inhibition. Panc1 cells were transiently transfected twice on two consecutive days with 50 nM of control (ctrl) miR or a miR-370-3p mimic and 24 h after the second round of transfection remained unstimulated (0) or were stimulated with TGFβ1 (5 ng/mL) for 72 h. Following TGFβ1 stimulation, cells were detached and viable cells counted. Data represent the mean ± SD of three independent experiments (n = 3). The number of non-TGFβ1-treated control cells were set arbitrarily at 100%. The asterisk (*) indicates significance (p < 0.05).