Table 1.
Obese Asthma Phenotypes | Early-Onset Asthma | Late-Onset Asthma |
---|---|---|
Age at onset | <12 years | >12 years |
Gender | Female = Male | Female > Male |
Airway function (FEV1, FVC) | Severe decrease in airway function | Minimal airway obstruction |
Nature | Atopic | Non-atopic |
Airway hyperreactivity | Severe airway Hyperresponsiveness | Less airway Hyperresponsiveness |
Symptom score | High symptom score | Low symptom score |
Airway inflammation | Eosinophilic airway infiltration | Neutrophilic infiltration |
Th1-Th2 profile | High Th2 biomarkers | Low Th2 biomarkers |